Spi-C Rabbit Polyclonal Antibody

The protein encoded by this gene regulates the development of red pulp macrophages, which are necessary for iron homeostasis and the recycling of red blood cells. [provided by RefSeq, Aug 2016], function:Probable transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer., similarity:Belongs to the ETS family., similarity:Contains 1 ETS DNA-binding domain., subunit:Binds DNA as a monomer., tissue specificity:Preferentially detected in fetal and adult spleen, lymph nodes and at lower levels in bone marrow and fetal liver.