LOK Rabbit Polyclonal Antibody
Product Specifications
Background
This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. [provided by RefSeq, Jul 2008], catalytic activity:ATP + a protein = ADP + a phosphoprotein., function:Can act on substrates such as myelin basic protein and histone 2A on serine and threonine residues., PTM:Autophosphorylated., similarity:Belongs to the protein kinase superfamily., similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily., similarity:Contains 1 protein kinase domain., tissue specificity:Expressed predominantly in lymphoid organs.
Product Name Alternative
STK10; LOK; Serine/threonine-protein kinase 10; Lymphocyte-oriented kinase
Gene Name
STK10
Gene ID
6793
Swiss Prot
O94804
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:2000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
120kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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