IP Receptor Rabbit Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor. [provided by RefSeq, Jul 2008], function:Receptor for prostacyclin (prostaglandin I2 or PGI2) . The activity of this receptor is mediated by G (s) proteins which activate adenylate cyclase., PTM:Isoprenylation does not influence ligand binding but is required for efficient coupling to the effectors adenylyl cyclase and phospholipase C., PTM:Palmitoylation of either Cys-308 or Cys-311 is sufficient to maintain functional coupling to G (s) and signaling., similarity:Belongs to the G-protein coupled receptor 1 family.
Product Name Alternative
PTGIR; PRIPR; Prostacyclin receptor; Prostaglandin I2 receptor; PGI receptor; PGI2 receptor; Prostanoid IP receptor
Gene Name
PTGIR
Gene ID
5739
Swiss Prot
P43119
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ELISA
Field of Research
Neuroactive ligand-receptor interaction; Vascular smooth muscle contraction
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:50-1:300, ELISA 1:2000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
45kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
