ZNF460 Rabbit Polyclonal Antibody

Zinc finger protein 460 (ZNF460) Homo sapiens Zinc finger proteins, such as ZNF272, interact with nucleic acids and have diverse functions. The zinc finger domain is a conserved amino acid sequence motif containing 2 specifically positioned cysteines and 2 histidines that are involved in coordinating zinc. Kruppel-related proteins form 1 family of zinc finger proteins. See ZFP93 (MIM 604749) for additional information on zinc finger proteins.[supplied by OMIM, May 2004], function:May be involved in transcriptional regulation., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the krueppel C2H2-type zinc-finger protein family., similarity:Contains 1 KRAB domain., similarity:Contains 11 C2H2-type zinc fingers., tissue specificity:Ubiquitously expressed at low levels. Highest levels are found in pancreas and liver.