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GDF-3 Rabbit Polyclonal Antibody

Product Specifications

Background

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role ocular and skeletal development. Mutations in this gene are associated with microphthalmia, coloboma, and skeletal abnormalities in human patients. [provided by RefSeq, Aug 2016], online information:GDF3 entry, similarity:Belongs to the TGF-beta family., subunit:Homodimer or heterodimer (Potential) . But, in contrast to other members of this family, cannot be disulfide-linked.

Product Name Alternative

GDF3; Growth/differentiation factor 3; GDF-3

Gene Name

GDF3

Gene ID

9573

Swiss Prot

Q9NR23

Host

Rabbit

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, ELISA

Purification

Affinity purification

Dilution

WB 1:500-1:2000, ELISA 1:5000-1:20000

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Modification

Unmodified

Molecular Weight

41kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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