CYP3A7 Rabbit Polyclonal Antibody

This gene encodes a member of the cytochrome P450 superfamily of enzymes, which participate in drug metabolism and the synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. This gene is part of a cluster of related genes on chromosome 7q21.1. Naturally-occurring readthrough transcription occurs between this gene and the downstream CYP3A51P pseudogene and is represented by GeneID:100861540. [provided by RefSeq, Jan 2015], catalytic activity:RH + reduced flavoprotein + O (2) = ROH + oxidized flavoprotein + H (2) O., cofactor:Heme group., function:Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics., induction:P450 can be induced to high levels in liver and other tissues by various foreign compounds, including drugs, pesticides, and carcinogens., online information:CYP3A7 alleles, similarity:Belongs to the cytochrome P450 family.

Steroid hormone biosynthesis; Linoleic acid metabolism; Retinol metabolism; Metabolism of xenobiotics by cytochrome P450; Drug metabolism; Drug metabolism