Calpain 12 Rabbit Polyclonal Antibody

The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes a member of the calpain large subunit family. [provided by RefSeq, Jun 2012], catalytic activity:Broad endopeptidase specificity., function:Calcium-regulated non-lysosomal thiol-protease., similarity:Belongs to the peptidase C2 family., similarity:Contains 1 calpain catalytic domain., similarity:Contains 1 EF-hand domain.