C9 Rabbit Polyclonal Antibody
Product Specifications
Background
This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC) . The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency. [provided by RefSeq, Feb 2009], disease:Defects in C9 are a cause of component C9 deficiency (C9D) [MIM:120940]. Patients with C9D suffer from recurrent bacterial infections, predominantly from Neisseria meningitidis., function:C9 is the final component of the complement system to be added in the assembly of the membrane attack complex. It is able to enter lipid bilayers, forming transmembrane channels., online information:C9 mutation db, PTM:Thrombin cleaves factor C9 to produce C9a and C9b., similarity:Belongs to the complement C6/C7/C8/C9 family., similarity:Contains 1 EGF-like domain., similarity:Contains 1 LDL-receptor class A domain., similarity:Contains 1 MACPF domain., similarity:Contains 1 TSP type-1 domain.
Product Name Alternative
C9; Complement component C9
Gene Name
C9
Gene ID
735
Swiss Prot
P02748
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ELISA
Field of Research
Complement and coagulation cascades; Prion diseases; Systemic lupus erythematosus
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ELISA 1:20000-1:40000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
70kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Product Datasheet
https://assets.enkilife.com/files/antibody/APRab07761_Enkilife_EN.pdf
Isotype
IgG
Available Sizes
Curated Selection
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