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Reg IV Rabbit Polyclonal Antibody

Product Specifications

Background

Function:May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium., induction:Up-regulated by mucosal injury from active Crohn's disease or ulcerative colitis. Up-regulated in colorectal tumors. Up-regulated in epithelial cells at regenerating margins of peptic ulcers in the stomach and duodenum., online information:Regenerating protein IV, similarity:Contains 1 C-type lectin domain., tissue specificity:Highly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentialy expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells., function:May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium., induction:Up-regulated by mucosal injury from active Crohn's disease or ulcerative colitis. Up-regulated in colorectal tumors. Up-regulated in epithelial cells at regenerating margins of peptic ulcers in the stomach and duodenum., online information:Regenerating protein IV, similarity:Contains 1 C-type lectin domain., tissue specificity:Highly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentialy expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells.

Product Name Alternative

REG4; GISP; RELP; Regenerating islet-derived protein 4; REG-4; Gastrointestinal secretory protein; REG-like protein; Regenerating islet-derived protein IV; Reg IV

Gene Name

REG4

Gene ID

83998

Swiss Prot

Q9BYZ8

Host

Rabbit

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

IHC, ICC/IF, ELISA

Purification

Affinity purification

Dilution

IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:20000-1:40000

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Modification

Unmodified

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

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