AOX1 Rabbit Polyclonal Antibody

Aldehyde oxidase produces hydrogen peroxide and, under certain conditions, can catalyze the formation of superoxide. Aldehyde oxidase is a candidate gene for amyotrophic lateral sclerosis. [provided by RefSeq, Jul 2008], catalytic activity:An aldehyde + H (2) O + O (2) = a carboxylic acid + H (2) O (2) ., caution:Was originally (PubMed:8248161) thought to be a xanthine dehydrogenase., cofactor:Binds 2 2Fe-2S clusters., cofactor:FAD., cofactor:Molybdopterin., similarity:Belongs to the xanthine dehydrogenase family., similarity:Contains 1 2Fe-2S ferredoxin-type domain., similarity:Contains 1 FAD-binding PCMH-type domain., subunit:Homodimer., tissue specificity:Abundant in liver, lower levels in lung, skeletal muscle, pancreas. Undetected in heart, brain and kidney.

Valine; leucine and isoleucine degradation; Tyrosine metabolism; Tryptophan metabolism; Vitamin B6 metabolism; Nicotinate and nicotinamide metabolism; Drug metabolism