Nur77 (phospho Ser351) Rabbit Polyclonal Antibody

This gene encodes a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. The encoded protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011], function:Orphan nuclear receptor., induction:By growth-stimulating agents., similarity:Belongs to the nuclear hormone receptor family., similarity:Belongs to the nuclear hormone receptor family. NR4 subfamily., similarity:Contains 1 nuclear receptor DNA-binding domain., subunit:Interacts with GADD45GIP1., tissue specificity:Fetal muscle and adult liver, brain and thyroid.

NR4A1; GFRP1; HMR; NAK1; Nuclear receptor subfamily 4 group A member 1; Early response protein NAK1; Nuclear hormone receptor NUR/77; Nur77; Orphan nuclear receptor HMR; Orphan nuclear receptor TR3; ST-59; Testicular receptor 3