ZDHHC9 Rabbit Polyclonal Antibody

This gene encodes an integral membrane protein that is a member of the zinc finger DHHC domain-containing protein family. The encoded protein forms a complex with golgin subfamily A member 7 and functions as a palmitoyltransferase. This protein specifically palmitoylates HRAS and NRAS. Mutations in this gene are associated with X-linked mental retardation. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, May 2010], catalytic activity:Palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA., domain:The DHHC domain is required for palmitoyltransferase activity., function:The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS., similarity:Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily., similarity:Contains 1 DHHC-type zinc finger., subunit:Interacts with GOLGA7., tissue specificity:Highly expressed in kidney, skeletal muscle, brain, lung and liver. Absent in thymus, spleen and leukocytes.

ZDHHC9; CXorf11; ZDHHC10; ZNF379; ZNF380; CGI-89; Palmitoyltransferase ZDHHC9; Zinc finger DHHC domain-containing protein 9; DHHC-9; DHHC9; Zinc finger protein 379; Zinc finger protein 380