Fibulin-2 Rabbit Polyclonal Antibody

This gene encodes an extracellular matrix protein, which belongs to the fibulin family. This protein binds various extracellular ligands and calcium. It may play a role during organ development, in particular, during the differentiation of heart, skeletal and neuronal structures. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008], developmental stage:Widely expressed during embryonic development. Primarily detected within the neuropithelium, spinal ganglia and peripheral nerves., function:Its binding to fibronectin and some other ligands is calcium dependent., similarity:Belongs to the fibulin family., similarity:Contains 11 EGF-like domains., similarity:Contains 3 anaphylatoxin-like domains., subunit:Homotrimer; disulfide-linked. Interacts with LAMA2., tissue specificity:Component of both basement membranes and other connective tissues. Expressed in heart, placenta and ovary.