LRRC41 Rabbit Polyclonal Antibody
Product Specifications
Background
Caution:It is uncertain whether Met-1 or Met-23 is the initiator., domain:The elongin BC complex binding domain is also known as BC-box with the consensus [APST]-L-x (3) -C-x (3) -[AILV]., function:Probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins., pathway:Protein modification; protein ubiquitination., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., sequence caution:Translation N-terminally extended., similarity:Contains 7 LRR (leucine-rich) repeats., subunit:Part of an E3 ubiquitin-protein ligase complex with Elongin BC (TCEB1 and TCEB2), RBX1 and CUL5. Component of a probable ECS (LRRC41) complex which contains CUL5, RNF7/RBX2, Elongin BC and LRRC41. Interacts with CUL5, RNF7, TCEB1 and TCEB2., caution:It is uncertain whether Met-1 or Met-23 is the initiator., domain:The elongin BC complex binding domain is also known as BC-box with the consensus [APST]-L-x (3) -C-x (3) -[AILV]., function:Probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins., pathway:Protein modification; protein ubiquitination., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., sequence caution:Translation N-terminally extended., similarity:Contains 7 LRR (leucine-rich) repeats., subunit:Part of an E3 ubiquitin-protein ligase complex with Elongin BC (TCEB1 and TCEB2), RBX1 and CUL5. Component of a probable ECS (LRRC41) complex which contains CUL5, RNF7/RBX2, Elongin BC and LRRC41. Interacts with CUL5, RNF7, TCEB1 and TCEB2.
Product Name Alternative
LRRC41; MUF1; PP7759; Leucine-rich repeat-containing protein 41; Protein Muf1
Gene Name
LRRC41
Gene ID
10489
Swiss Prot
Q15345
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:5000-1:10000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
80kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
