CHSY2 Rabbit Polyclonal Antibody
Product Specifications
Background
Catalytic activity:UDP-alpha-D-glucuronate + N-acetyl-beta-D-galactosaminyl- (1->4) -beta-D-glucuronosyl-proteoglycan = UDP + beta-D-glucuronosyl- (1->3) -N-acetyl-beta-D-galactosaminyl- (1->4) -beta-D-glucuronosyl-proteoglycan., catalytic activity:UDP-N-acetyl-D-galactosamine + beta-D-glucuronosyl- (1->3) -N-acetyl-beta-D-galactosaminyl-proteoglycan = UDP + N-acetyl-beta-D-galactosaminyl- (1->4) -beta-D-glucuronosyl- (1->3) -N-acetyl-beta-D-galactosaminyl-proteoglycan., cofactor:Divalent cations. Highest activities are measured with manganese. Can also utilize cobalt., function:Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer., online information:GlycoGene database, PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the chondroitin N-acetylgalactosaminyltransferase family., subunit:Binds CHSY1., tissue specificity:Ubiquitous. Highly expressed in pancreas, ovary, brain, heart, skeletal muscle, colon, kidney, liver, stomach, small intestine and placenta., catalytic activity:UDP-alpha-D-glucuronate + N-acetyl-beta-D-galactosaminyl- (1->4) -beta-D-glucuronosyl-proteoglycan = UDP + beta-D-glucuronosyl- (1->3) -N-acetyl-beta-D-galactosaminyl- (1->4) -beta-D-glucuronosyl-proteoglycan., catalytic activity:UDP-N-acetyl-D-galactosamine + beta-D-glucuronosyl- (1->3) -N-acetyl-beta-D-galactosaminyl-proteoglycan = UDP + N-acetyl-beta-D-galactosaminyl- (1->4) -beta-D-glucuronosyl- (1->3) -N-acetyl-beta-D-galactosaminyl-proteoglycan., cofactor:Divalent cations. Highest activities are measured with manganese. Can also utilize cobalt., function:Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer., online information:GlycoGene database, PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the chondroitin N-acetylgalactosaminyltransferase family., subunit:Binds CHSY1., tissue specificity:Ubiquitous. Highly expressed in pancreas, ovary, brain, heart, skeletal muscle, colon, kidney, liver, stomach, small intestine and placenta.
Product Name Alternative
CHPF; CSS2; Chondroitin sulfate synthase 2; Chondroitin glucuronyltransferase 2; Chondroitin-polymerizing factor; ChPF; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II; N-acetylgalactosaminyl-pro
Gene Name
CHPF
Gene ID
79586
Swiss Prot
Q8IZ52
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Field of Research
Chondroitin sulfate biosynthesis
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:200-1:1000, ELISA 1:20000-1:40000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
85kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Frequently Asked Questions
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