GABA T-1 Rabbit Polyclonal Antibody

The SLC6A1 gene encodes a gamma-aminobutyric acid (GABA) transporter, which removes GABA from the synaptic cleft (Hirunsatit et al., 2009 [PubMed 19077666]) .[supplied by OMIM, Jul 2009], domain:The PDZ domain-binding motif is involved in the interaction with MPP5., function:Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals., miscellaneous:This protein is the target of psychomotor stimulants such as amphetamines or cocaine., similarity:Belongs to the sodium:neurotransmitter symporter (SNF) family., subcellular location:Localized at the plasma membrane and in a subset of intracellular vesicles. Localized at the presynaptic terminals of interneurons., subunit:Interacts with MPP5.