GABA T-1 Rabbit Polyclonal Antibody
Product Specifications
Background
The SLC6A1 gene encodes a gamma-aminobutyric acid (GABA) transporter, which removes GABA from the synaptic cleft (Hirunsatit et al., 2009 [PubMed 19077666]) .[supplied by OMIM, Jul 2009], domain:The PDZ domain-binding motif is involved in the interaction with MPP5., function:Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals., miscellaneous:This protein is the target of psychomotor stimulants such as amphetamines or cocaine., similarity:Belongs to the sodium:neurotransmitter symporter (SNF) family., subcellular location:Localized at the plasma membrane and in a subset of intracellular vesicles. Localized at the presynaptic terminals of interneurons., subunit:Interacts with MPP5.
Product Name Alternative
Sodium- and chloride-dependent GABA transporter 1 (GAT-1; Solute carrier family 6 member 1)
Gene Name
SLC6A1 GABATR GABT1 GAT1
Gene ID
6529
Swiss Prot
P30531
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:50-1:200, ICC/IF 1:50-1:200, ELISA 1:10000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
50kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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