CGKII Rabbit Polyclonal Antibody

This gene encodes a protein that belongs to the serine/threonine protein kinase family of proteins. The encoded protein plays a role in the regulation of fluid balance in the intestine. A similar protein in mouse is thought to regulate differentiation and proliferation of cells in the colon. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013], catalytic activity:ATP + a protein = ADP + a phosphoprotein., enzyme regulation:Binding of cGMP results in enzyme activation., similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily., similarity:Contains 1 AGC-kinase C-terminal domain., similarity:Contains 1 protein kinase domain., similarity:Contains 2 cyclic nucleotide-binding domains., tissue specificity:Highly concentrated in brain, lung and intestinal mucosa.