Calretinin Rabbit Polyclonal Antibody

This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010], function:Calretinin is a calcium-binding protein which is abundant in auditory neurons., online information:Calbindin entry, similarity:Belongs to the calbindin family., similarity:Contains 6 EF-hand domains., tissue specificity:Brain.