Calbindin D28K Rabbit Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the calcium-binding protein superfamily that includes calmodulin and troponin C. Originally described as a 27 kDa protein, it is now known to be a 28 kDa protein. It contains four active calcium-binding domains, and has two modified domains that are thought to have lost their calcium binding capability. This protein is thought to buffer entry of calcium upon stimulation of glutamate receptors. Depletion of this protein was noted in patients with Huntington disease. [provided by RefSeq, Jan 2015], domain:This protein has four functional calcium-binding sites; potential sites II and VI have lost affinity for calcium., function:Buffers cytosolic calcium. May stimulate a membrane Ca (2+) -ATPase and a 3',5'-cyclic nucleotide phosphodiesterase., online information:Calbindin entry, similarity:Belongs to the calbindin family., similarity:Contains 5 EF-hand domains., subunit:Interacts with RANBP9.
Product Name Alternative
CALB1; CAB27; Calbindin; Calbindin D28; D-28K; Vitamin D-dependent calcium-binding protein, avian-type
Gene Name
CALB1
Gene ID
793
Swiss Prot
P05937
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:10000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
30kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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