AIM2 Rabbit Polyclonal Antibody
Product Specifications
Background
AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2. [provided by RefSeq, Jul 2008], disease:Defects in AIM2 may be a cause of microsatellite unstable colon cancers., function:Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity., induction:By interferon gamma., similarity:Belongs to the HIN-200 family., similarity:Contains 1 DAPIN domain., similarity:Contains 1 HIN-200 domain., subunit:Homodimer., tissue specificity:Expressed in spleen, small intestine, peripheral blood leukocytes, and testis.
Product Name Alternative
AIM2; Interferon-inducible protein AIM2; Absent in melanoma 2
Gene Name
AIM2
Gene ID
9447
Swiss Prot
O14862
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Field of Research
Cytosolic DNA-sensing pathway
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:200-1:1000, ELISA 1:20000-1:40000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
39kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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