Neuroglycan C Rabbit Polyclonal Antibody

The protein encoded by this gene is a proteoglycan that may function as a neural growth and differentiation factor. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011], developmental stage:Expressed in brain of 3 months, 5 and 10-year-old individuals., function:May function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation., miscellaneous:Different forms of various molecular weight have been observed. Such forms are possibly due to different levels of glycosylation, phosphorylation and/or protein cleavage., PTM:N-glycosylated., PTM:O-glycosylated; contains chondroitin sulfate glycans. Part-time proteoglycan, expressed in part as a proteoglycan exhibiting chondroitin sulfate glycans and in part as a non-proteoglycan form. The relative amount of both forms depends on tissues and tissues maturation., PTM:Phosphorylated; in intracellular and extracellular parts., similarity:Contains 1 EGF-like domain., subcellular location:In neurons, localizes to synaptic junctions (By similarity) . Also detected in the endoplasmic reticulum and the Golgi (By similarity) . Partially enriched in lipid rafts., subunit:Binds TNR and probably TNC (By similarity) . Interacts with ERBB3 and GOPC., tissue specificity:Restricted to brain (at protein level) .