GAP1-InsP4 BP Rabbit Polyclonal Antibody

This gene encodes a protein that binds inositol 1,3,4,5-tetrakisphosphate and stimulates the GTPase activity of Ras p21. This protein functions as a negative regulator of the Ras signalling pathway. It is localized to the cell membrane via a pleckstrin homology (PH) domain in the C-terminal region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016], function:Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4) with high affinity. Might be a specific IP4 receptor., similarity:Contains 1 Btk-type zinc finger., similarity:Contains 1 PH domain., similarity:Contains 1 Ras-GAP domain., similarity:Contains 2 C2 domains.