GABAA Rα6 Rabbit Polyclonal Antibody

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008], function:GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel., online information:Forbidden fruit - Issue 56 of March 2005, similarity:Belongs to the ligand-gated ionic channel (TC 1.A.9) family., subunit:Binds UBQLN1 (By similarity) . Generally pentameric. There are five types of GABA (A) receptor chains: alpha, beta, gamma, delta, and rho.