FRP-2 Rabbit Polyclonal Antibody
Product Specifications
Background
This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer. [provided by RefSeq, Jul 2008], domain:The FZ domain is involved in binding with Wnt ligands., function:Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis., similarity:Belongs to the secreted frizzled-related protein (sFRP) family., similarity:Contains 1 FZ (frizzled) domain., similarity:Contains 1 NTR domain., tissue specificity:Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon.
Product Name Alternative
SFRP2; FRP2; SARP1; FKSG12; Secreted frizzled-related protein 2; FRP-2; sFRP-2; Secreted apoptosis-related protein 1; SARP-1
Gene Name
SFRP2
Gene ID
6423
Swiss Prot
Q96HF1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ELISA
Field of Research
WNT; WNT-T CELL
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ELISA 1:5000-1:10000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
30kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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