BTF Rabbit Polyclonal Antibody

This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008], function:Death-promoting transcriptional repressor., sequence caution:Contaminating sequence. Potential poly-A sequence., subunit:Interacts with Bcl-2 related proteins, EMD, with the adenovirus E1B 19 kDa protein and with DNA., tissue specificity:Ubiquitous.