USP11 Rabbit Polyclonal Antibody

Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This gene encodes a deubiquitinating enzyme which lies in a gene cluster on chromosome Xp11.23 [provided by RefSeq, Jul 2008], catalytic activity:Ubiquitin C-terminal thioester + H (2) O = ubiquitin + a thiol., similarity:Belongs to the peptidase C19 family., similarity:Contains 1 DUSP domain., subunit:Interacts with RANBP9/RANBPM.

USP11; UHX1; Ubiquitin carboxyl-terminal hydrolase 11; Deubiquitinating enzyme 11; Ubiquitin thioesterase 11; Ubiquitin-specific-processing protease 11