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Dvl-3 Rabbit Polyclonal Antibody

Product Specifications

Background

This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation. [provided by RefSeq, Jul 2008], function:May play a role in the signal transduction pathway mediated by multiple Wnt genes., similarity:Belongs to the DSH family., similarity:Contains 1 DEP domain., similarity:Contains 1 DIX domain., similarity:Contains 1 PDZ (DHR) domain., subunit:Interacts (via the PDZ domain) with the C-terminal regions of VANGL1 and VANGL2 (By similarity) . Interacts (via the region containing both the PDZ and DEP domains) with LRRFIP2; the DIX domain may inhibit this interaction.

Product Name Alternative

DVL3; KIAA0208; Segment polarity protein dishevelled homolog DVL-3; Dishevelled-3; DSH homolog 3

Gene Name

DVL3

Gene ID

1857

Swiss Prot

Q92997

Host

Rabbit

Reactivity

Human, Mouse

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, ELISA

Field of Research

WNT; WNT-T CELLNotch; Melanogenesis; Pathways in cancer; Colorectal cancer; Basal cell carcinoma

Purification

Affinity purification

Dilution

WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:10000-1:20000

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Modification

Unmodified

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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