Dvl-3 Rabbit Polyclonal Antibody
Product Specifications
Background
This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation. [provided by RefSeq, Jul 2008], function:May play a role in the signal transduction pathway mediated by multiple Wnt genes., similarity:Belongs to the DSH family., similarity:Contains 1 DEP domain., similarity:Contains 1 DIX domain., similarity:Contains 1 PDZ (DHR) domain., subunit:Interacts (via the PDZ domain) with the C-terminal regions of VANGL1 and VANGL2 (By similarity) . Interacts (via the region containing both the PDZ and DEP domains) with LRRFIP2; the DIX domain may inhibit this interaction.
Product Name Alternative
DVL3; KIAA0208; Segment polarity protein dishevelled homolog DVL-3; Dishevelled-3; DSH homolog 3
Gene Name
DVL3
Gene ID
1857
Swiss Prot
Q92997
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Field of Research
WNT; WNT-T CELLNotch; Melanogenesis; Pathways in cancer; Colorectal cancer; Basal cell carcinoma
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:10000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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