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AF-10 Rabbit Polyclonal Antibody

Product Specifications

Background

Myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10 (MLLT10) Homo sapiens This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010], disease:A chromosomal aberration involving MLLT10 is associated with acute leukemias. Translocation t (10;11) (p12; q23) with MLL/HRX. The result is a rogue activator protein., disease:A chromosomal aberration involving MLLT10 is associated with diffuse histiocytic lymphomas. Translocation t (10;11) (p13; q14) with PICALM., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 2 PHD-type zinc fingers., tissue specificity:Expressed abundantly in testis.

Product Name Alternative

MLLT10; AF10; Protein AF-10; ALL1-fused gene from chromosome 10 protein

Gene Name

MLLT10

Gene ID

8028

Swiss Prot

P55197

Host

Rabbit

Reactivity

Human, Mouse

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, ELISA

Purification

Affinity purification

Dilution

WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Modification

Unmodified

Molecular Weight

109kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Product Datasheet

https://assets.enkilife.com/files/antibody/APRab06656_Enkilife_EN.pdf

Isotype

IgG

Available Sizes

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