AF-10 Rabbit Polyclonal Antibody
Product Specifications
Background
Myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10 (MLLT10) Homo sapiens This gene encodes a transcription factor and has been identified as a partner gene involved in several chromosomal rearrangements resulting in various leukemias. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010], disease:A chromosomal aberration involving MLLT10 is associated with acute leukemias. Translocation t (10;11) (p12; q23) with MLL/HRX. The result is a rogue activator protein., disease:A chromosomal aberration involving MLLT10 is associated with diffuse histiocytic lymphomas. Translocation t (10;11) (p13; q14) with PICALM., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 2 PHD-type zinc fingers., tissue specificity:Expressed abundantly in testis.
Product Name Alternative
MLLT10; AF10; Protein AF-10; ALL1-fused gene from chromosome 10 protein
Gene Name
MLLT10
Gene ID
8028
Swiss Prot
P55197
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:200-1:1000, ELISA 1:5000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
109kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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