A Cyclase I Rabbit Polyclonal Antibody

This gene encodes a member of the of adenylate cyclase gene family that is primarily expressed in the brain. This protein is regulated by calcium/calmodulin concentration and may be involved in brain development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013], catalytic activity:ATP = 3',5'-cyclic AMP + diphosphate., cofactor:Binds 2 magnesium ions per subunit., enzyme regulation:Activated by calcium/calmodulin. Inhibited by the G protein beta and gamma subunit complex., function:This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning., similarity:Belongs to the adenylyl cyclase class-4/guanylyl cyclase family., similarity:Contains 2 guanylate cyclase domains., tissue specificity:Brain, retina and adrenal medulla.

ADCY1; Adenylate cyclase type 1; ATP pyrophosphate-lyase 1; Adenylate cyclase type I; Adenylyl cyclase 1; Ca (2+) /calmodulin-activated adenylyl cyclase

Purine metabolism; Calcium; Chemokine; Oocyte meiosis; Vascular smooth muscle contraction; Gap junction; Long-term potentiation; GnRH; Progesterone-mediated oocyte maturation; Melanogenesis; Dilated cardiomyopathy