NDUFS3 Rabbit Polyclonal Antibody
Product Specifications
Background
This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I) . Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.[provided by RefSeq, Apr 2009], catalytic activity:NADH + acceptor = NAD (+) + reduced acceptor., catalytic activity:NADH + ubiquinone = NAD (+) + ubiquinol., function:Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone., similarity:Belongs to the complex I 30 kDa subunit family., subunit:Mammalian complex I is composed of 45 different subunits.
Product Name Alternative
NDUFS3; NADH dehydrogenase [ubiquinone] iron-sulfur protein 3; mitochondrial; Complex I-30kD; CI-30kD; NADH-ubiquinone oxidoreductase 30 kDa subunit
Gene Name
NDUFS3
Gene ID
4722
Swiss Prot
O75489
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, ELISA
Field of Research
Oxidative phosphorylation; Alzheimer's disease; Parkinson's disease; Huntington's disease
Purification
Affinity purification
Dilution
WB 1:500-1:2000, ELISA 1:20000-1:40000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
40kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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