ABCA8 Rabbit Polyclonal Antibody

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The encoded protein may regulate lipid metabolism and be involved in the formation and maintenance of myelin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014], function:ATP-dependent lipophilic drug transporter., similarity:Belongs to the ABC transporter family. ABCA subfamily., similarity:Contains 2 ABC transporter domains., tissue specificity:Widely expressed with higher expression in heart, skeletal muscle and liver.