PI 3-Kinase p85β Rabbit Polyclonal Antibody

Phosphatidylinositol 3-kinase (PI3K) is a lipid kinase that phosphorylates phosphatidylinositol and similar compounds, creating second messengers important in growth signaling pathways. PI3K functions as a heterodimer of a regulatory and a catalytic subunit. The protein encoded by this gene is a regulatory component of PI3K. Two transcript variants, one protein coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Dec 2012], function:Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane., similarity:Belongs to the PI3K p85 subunit family., similarity:Contains 1 Rho-GAP domain., similarity:Contains 1 SH3 domain., similarity:Contains 2 SH2 domains., subunit:Heterodimer of a p110 (catalytic) and a p85 (regulatory) subunits.

P85; p85 beta; p85-BETA; P85B; P85B_HUMAN; Phosphatidylinositol 3 kinase; Phosphatidylinositol 3 kinase regulatory beta subunit; Phosphatidylinositol 3 kinase regulatory subunit beta; Phosphatidylinositol 3 kinase regulatory subunit polypeptide 2; Phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 2 (p85 beta) ; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta; phosphatidylinositol 3-kinase; Phosphatidylinositol 3-kinase regulatory beta subunit; Phosphatidylinositol 3-kinase regulatory subunit beta; Phosphoinositide 3 kinase regulatory subunit 2 (beta) ; Phosphoinositide 3 kinase regulatory subunit 2; Phosphoinositide 3 kinase regulatory subunit polypeptide 2 (p85 beta) ; Phosphoinositide 3 kinase regulatory subunit polypeptide 2; Phosphoinositide 3 kinase, regulatory subunit 2 (beta) ; Phosphoinositide 3 kinase, regulatory subunit 2 (p85 beta) ; PI3 kinase p85 beta subunit; PI3 kinase p85 subunit beta; PI3-kinase regulatory subunit beta; PI3-kinase subunit p85-beta; PI3K; PI3K regulatory subunit beta; PIK3R 2; PIK3R2; polypeptide 2 (p85 beta) ; PtdIns 3 kinase p85 beta; PtdIns-3-kinase p85-beta; PtdIns-3-kinase regulatory subunit beta; PtdIns-3-kinase regulatory subunit p85-beta.

ErbB_HER; Chemokine; Phosphatidylinositol signaling system; mTOR; Apoptosis_Inhibition; Apoptosis_Mitochondrial; Apoptosis_Overview; VEGF; Focal adhesion; Toll_Like; Jak_STAT; Natural killer cell mediated cytotoxicity; T_Cell_Receptor; B_Cell_Antigen; Fc epsilon RI; Fc gamma R-mediated phagocytosis; Leukocyte transendothelial migration; Neurotrophin; Regulates Actin and Cytoskeleton; Insulin_Receptor; Progesterone-mediated oocyte maturation; Type II diabetes mellitus; Aldosterone-regulated sodium reabsorption; Pathways in cancer; Colorectal cancer; Renal cell carcinoma; Pancreatic cancer; Endometrial cancer; Glioma; Prostate cancer; Melanoma; Chronic myeloid leukemia; Acute myeloid leukemia; Small cell lung cancer; Non-small cell lung cancer