SNAI 1 (phospho Ser246) Rabbit Polyclonal Antibody
Product Specifications
Background
Snail family transcriptional repressor 1 (SNAI1) Homo sapiens The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. [provided by RefSeq, Jul 2008], function:Seems to be involved in embryonic mesoderm formation. Binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription., similarity:Belongs to the snail C2H2-type zinc-finger protein family., similarity:Contains 4 C2H2-type zinc fingers., tissue specificity:Expressed in a variety of tissues with the highest expression in kidney.
Product Name Alternative
SNAI1; SNAH; Zinc finger protein SNAI1; Protein snail homolog 1; Protein sna
Gene Name
SNAI1
Gene ID
6615
Swiss Prot
O95863
Host
Rabbit
Reactivity
Human, Mouse, Monkey
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Field of Research
Adherens_Junction
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:200-1:1000, ELISA 1:5000-1:10000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Phosphorylated
Molecular Weight
29kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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