MAST4 Rabbit Polyclonal Antibody

This gene encodes a member of the microtubule-associated serine/threonine protein kinases. The proteins in this family contain a domain that gives the kinase the ability to determine its own scaffold to control the effects of their kinase activities. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014], catalytic activity:ATP + a protein = ADP + a phosphoprotein., caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data., cofactor:Magnesium., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family., similarity:Contains 1 AGC-kinase C-terminal domain., similarity:Contains 1 PDZ (DHR) domain., similarity:Contains 1 protein kinase domain., tissue specificity:Highly expressed in most normal human tissues, with an exception of in testis, small intestine, colon and peripheral blood leukocyte.