ACOT2 Rabbit Polyclonal Antibody

This gene encodes a member of the acyl-CoA thioesterase protein family, and is one of four acyl-CoA hydrolase genes located in a cluster on chromosome 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012], catalytic activity:Palmitoyl-CoA + H (2) O = CoA + palmitate., caution:Was originally (PubMed:10944470) thought to be peroxisomal but was later shown (PubMed:16940157) to be mitochondrial., function:Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Displays high levels of activity on medium- and long chain acyl CoAs., similarity:Belongs to the C/M/P thioester hydrolase family., tissue specificity:Strongest expression in heart, liver, muscle and kidney. Weak in placenta and pancreas.

ACOT2; PTE2; PTE2A; Acyl-coenzyme A thioesterase 2; mitochondrial; Acyl-CoA thioesterase 2; Acyl-coenzyme A thioester hydrolase 2a; CTE-Ia; Long-chain acyl-CoA thioesterase 2; ZAP128