HIPK4 Rabbit Polyclonal Antibody
Product Specifications
Background
Homeodomain interacting protein kinase 4 (HIPK4) Homo sapiens This gene encodes a member of the homeodomain interacting protein kinase (HIPK) family of proteins. While other members of this family are found throughout vertebrates, this member is present only in mammals. Compared to other members of this family, the encoded protein lacks a nuclear localization signal and a C-terminal autoinhibitory domain. The encoded protein exhibits kinase activity and may phosphorylate the tumor suppressor protein p53. [provided by RefSeq, Jul 2016], catalytic activity:ATP + a protein = ADP + a phosphoprotein., function:Protein kinase that phosphorylates human TP53 at Ser-9, and thus induces TP53 repression of BIRC5 promoter (By similarity) . May act as a corepressor of transcription factors ., PTM:Autophosphorylated., similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily., similarity:Contains 1 protein kinase domain.
Product Name Alternative
HIPK4; Homeodomain-interacting protein kinase 4
Gene Name
HIPK4
Gene ID
147746
Swiss Prot
Q8NE63
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:200-1:1000, ELISA 1:10000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
70kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Product Datasheet
https://assets.enkilife.com/files/antibody/APRab12036_Enkilife_EN.pdf
Isotype
IgG
Available Sizes
Curated Selection
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