Glycerate Kinase Rabbit Polyclonal Antibody

This locus encodes a member of the glycerate kinase type-2 family. The encoded enzyme catalyzes the phosphorylation of (R) -glycerate and may be involved in serine degradation and fructose metabolism. Decreased activity of the encoded enzyme may be associated with the disease D-glyceric aciduria. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009], catalytic activity:ATP + (R) -glycerate = ADP + 3-phospho- (R) -glycerate., disease:Defects in GLYCTK are the cause of D-glyceric acidemia [MIM:220120]. It is characterized by nonketotic hyperglycinemia with the excretion of D-glyceric acid in the urine and the presence of this substance in the serum., similarity:Belongs to the glycerate kinase type-2 family., tissue specificity:Widely expressed.