Glycerate Kinase Rabbit Polyclonal Antibody
Product Specifications
Background
This locus encodes a member of the glycerate kinase type-2 family. The encoded enzyme catalyzes the phosphorylation of (R) -glycerate and may be involved in serine degradation and fructose metabolism. Decreased activity of the encoded enzyme may be associated with the disease D-glyceric aciduria. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009], catalytic activity:ATP + (R) -glycerate = ADP + 3-phospho- (R) -glycerate., disease:Defects in GLYCTK are the cause of D-glyceric acidemia [MIM:220120]. It is characterized by nonketotic hyperglycinemia with the excretion of D-glyceric acid in the urine and the presence of this substance in the serum., similarity:Belongs to the glycerate kinase type-2 family., tissue specificity:Widely expressed.
Product Name Alternative
GLYCTK; HBEBP4; LP5910; Glycerate kinase; HBeAg-binding protein 4
Gene Name
GLYCTK
Gene ID
132158
Swiss Prot
Q8IVS8
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Field of Research
Glycine; serine and threonine metabolism; Glycerolipid metabolism; Glyoxylate and dicarboxylate metabolism
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:200-1:1000, ELISA 1:10000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
60kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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