HBP1 (phospho Ser402) Rabbit Polyclonal Antibody

Function:Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4., similarity:Contains 1 AXH domain., similarity:Contains 1 HMG box DNA-binding domain., subunit:Binds the second PAH repeat of SIN3A (By similarity) . Binds TCF4 and RB1., function:Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4., similarity:Contains 1 AXH domain., similarity:Contains 1 HMG box DNA-binding domain., subunit:Binds the second PAH repeat of SIN3A (By similarity) . Binds TCF4 and RB1.