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HBP1 (phospho Ser402) Rabbit Polyclonal Antibody

Product Specifications

Background

Function:Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4., similarity:Contains 1 AXH domain., similarity:Contains 1 HMG box DNA-binding domain., subunit:Binds the second PAH repeat of SIN3A (By similarity) . Binds TCF4 and RB1., function:Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4., similarity:Contains 1 AXH domain., similarity:Contains 1 HMG box DNA-binding domain., subunit:Binds the second PAH repeat of SIN3A (By similarity) . Binds TCF4 and RB1.

Product Name Alternative

HBP1; HMG box-containing protein 1; HMG box transcription factor 1; High mobility group box transcription factor 1

Gene Name

HBP1

Gene ID

26959

Swiss Prot

O60381

Host

Rabbit

Reactivity

Human, Rat, Mouse

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB, IHC, ICC/IF, ELISA

Purification

Affinity purification

Dilution

WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:5000-1:10000

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Modification

Phosphorylated

Molecular Weight

58kDa

Storage Conditions

Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.

Isotype

IgG

Available Sizes

Curated Selection

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