Oct-1 Rabbit Polyclonal Antibody
Product Specifications
Background
The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 [PubMed 8314572]) . Members of this family contain the POU domain, a 160-amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT.[supplied by OMIM, Jul 2010], function:Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR., PTM:Phosphorylated by PRKDC., similarity:Belongs to the POU transcription factor family. Class-2 subfamily., similarity:Contains 1 homeobox DNA-binding domain., similarity:Contains 1 POU-specific domain., subunit:Interacts with NR3C1, AR, PGR and HCFC1., tissue specificity:Ubiquitous. Isoform 2 is lymphocyte-specific.
Product Name Alternative
POU2F1; OCT1; OTF1; POU domain; class 2, transcription factor 1; NF-A1; Octamer-binding protein 1; Oct-1; Octamer-binding transcription factor 1; OTF-1
Gene Name
POU2F1
Gene ID
5451
Swiss Prot
P14859
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:5000-1:10000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
76kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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