EEF2K (phospho Ser366) Rabbit Polyclonal Antibody
Product Specifications
Background
This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment. [provided by RefSeq, Jul 2008], catalytic activity:ATP + [elongation factor 2] = ADP + [elongation factor 2] phosphate., enzyme regulation:Undergoes calcium/calmodulin-dependent intramolecular autophosphorylation, and this results in it becoming partially calcium/calmodulin-independent., function:Phosphorylates eukaryotic elongation factor-2. Binds calmodulin., similarity:Belongs to the protein kinase superfamily. Alpha-type protein kinase family., similarity:Contains 1 alpha-type protein kinase domain., subunit:Monomer or homodimer .
Product Name Alternative
EEF2K; Eukaryotic elongation factor 2 kinase; eEF-2 kinase; eEF-2K; Calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase
Gene Name
EEF2K
Gene ID
29904
Swiss Prot
O00418
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Field of Research
AMPK
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:20000-1:40000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Phosphorylated
Molecular Weight
105kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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