GABAA Rβ1 (phospho Ser434) Rabbit Polyclonal Antibody
Product Specifications
Background
The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 1 subunit. It is mapped to chromosome 4p12 in a cluster comprised of genes encoding alpha 4, alpha 2 and gamma 1 subunits of the GABA A receptor. Alteration of this gene is implicated in the pathogenetics of schizophrenia. [provided by RefSeq, Jul 2008], function:GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel., online information:Forbidden fruit - Issue 56 of March 2005, similarity:Belongs to the ligand-gated ionic channel (TC 1.A.9) family., subunit:Binds UBQLN1 (By similarity) . Generally pentameric. There are five types of GABA (A) receptor chains: alpha, beta, gamma, delta, and rho.
Product Name Alternative
GABRB1; Gamma-aminobutyric acid receptor subunit beta-1; GABA (A) receptor subunit beta-1
Gene Name
GABRB1
Gene ID
2560
Swiss Prot
P18505
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Field of Research
Neuroactive ligand-receptor interaction
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:20000-1:40000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Phosphorylated
Molecular Weight
55kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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