MST-3 Rabbit Polyclonal Antibody
Product Specifications
Background
This gene encodes a serine/threonine protein kinase that functions upstream of mitogen-activated protein kinase (MAPK) signaling. The encoded protein is cleaved into two chains by caspases; the N-terminal fragment (MST3/N) translocates to the nucleus and promotes programmed cells death. There is a pseudogene for this gene on chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013], catalytic activity:ATP + a protein = ADP + a phosphoprotein., cofactor:Manganese. Only isoform A requires manganese., function:Protein kinase that act on both serine and threonine residues., PTM:Autophosphorylated. Isoform B is activated by phosphorylation by PKA., similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily., similarity:Contains 1 protein kinase domain., tissue specificity:Isoform A is ubiquitous. Isoform B is expressed in brain with high expression in hippocampus and cerebral cortex.
Product Name Alternative
STK24; MST3; STK3; Serine/threonine-protein kinase 24; Mammalian STE20-like protein kinase 3; MST-3; STE20-like kinase MST3
Gene Name
STK24
Gene ID
8428
Swiss Prot
Q9Y6E0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:20000-1:40000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
50kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
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