IK Rabbit Polyclonal Antibody

The protein encoded by this gene was identified by its RED repeat, a stretch of repeated arginine, glutamic acid and aspartic acid residues. The protein localizes to discrete dots within the nucleus, excluding the nucleolus. Its function is unknown. This gene maps to chromosome 5; however, a pseudogene may exist on chromosome 2. [provided by RefSeq, Jul 2008], caution:Was originally (PubMed:7970704) thought to be the IK factor, a cytokine involved in the negative regulatory pathway of constitutive MHC class II antigens expression., developmental stage:Expressed at similar levels in fetal and adult tissues., function:Not known. May bind to chromatin., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the RED family., tissue specificity:Ubiquitous.