Chr-A Rabbit Polyclonal Antibody
Product Specifications
Background
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Two other peptides, catestatin and chromofungin, have antimicrobial activity and antifungal activity, respectively. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014], function:Pancreastatin strongly inhibits glucose induced insulin release from the pancreas., miscellaneous:Binds calcium with a low-affinity., PTM:Sulfated on tyrosine residues and/or contains sulfated glycans., similarity:Belongs to the chromogranin/secretogranin protein family., subcellular location:Neuroendocrine and endocrine secretory granules.
Product Name Alternative
CHGA; Chromogranin-A; CgA; Pituitary secretory protein I; SP-I
Gene Name
CHGA
Gene ID
1113
Swiss Prot
P10645
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:5000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
68kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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