Sox-8/9/17/18 Rabbit Polyclonal Antibody
Product Specifications
Background
SRY-box 8 (SOX8) Homo sapiens This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein may be involved in brain development and function. Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome) . [provided by RefSeq, Jul 2008], function:May play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3'., similarity:Contains 1 HMG box DNA-binding domain.
Product Name Alternative
SOX8; Transcription factor SOX-8; SOX9; Transcription factor SOX-9; SOX17; Transcription factor SOX-17; SOX18; Transcription factor SOX-18
Gene Name
SOX8/9/17/18
Gene ID
30812/6662/64321/54345
Swiss Prot
P57073/P48436/Q9H6I2/P35713
Host
Rabbit
Reactivity
Human, Mouse, Monkey
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB, IHC, ICC/IF, ELISA
Field of Research
WNT; WNT-T CELL; β-Catenin
Purification
Affinity purification
Dilution
WB 1:500-1:2000, IHC 1:100-1:300, ICC/IF 1:50-1:200, ELISA 1:5000-1:20000
Form
Liquid
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Modification
Unmodified
Molecular Weight
47kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.
Isotype
IgG
Available Sizes
Curated Selection
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